MAD SSCi Meeting Agenda

Monday Pre Conference Workshops
Time Presentation Title Room
Mon
3:00pm to 5:00pm
Vendor Preconference TBD

Qiagen Inc.
Waterfront Room, WPH
Opening Reception
Time Presentation Title Room
Mon
6:00pm to 6:30pm
About the ABRF

Frances Weis-Garcia Ph.D.
ABRF President
Memorial Sloan Kettering Cancer Center
Museum Education Center
Mon
6:30pm to 7:30pm
Featured presentation and tours of WVU's art collection

Julie Brefczynski-Lewis, Ph.D.
Assitant Professor
Blanchette Rockefeller Neurosciences Institute, West Virginia University
Museum Education Center
Tuesday Breakfast and Exhibits
Time Presentation Title Room
Tue
8:00am to 9:00am
Breakfast with the Exhibitors

MEC Lobby
Welcome and Keynote
Time Presentation Title Room
Tue
9:00am to 10:00am
Welcome

Trina Wafle
MAD SSCi President, Shared Research Facilities Director
West Virginia University Shared Research Facilities
Salon E-H, WPH
Tue
9:00am to 10:00am
Putting the ‘Epigenomics’ in Autism Epidemiology

Christine Ladd Acosta, Ph.D.
Assistant Professor
Wendy Klag Center for Autism and Developmental Disabilities, Johns Hopkins Bloomberg School of Public Health
Salon E-H, WPH
Tuesday Morning Concurrent Sessions
Time Presentation Title Room
Tue
10:15am to 12:15pm
QC at the Bench

Belynda Hicks, M.S.
Deputy Director, Cancer Genomics Research Laboratory
National Cancer Institute
NOTE: this session will be repeated in the afternoon. Content is the same for both sessions.
Waterfront Room, WPH
Tue
10:15am to 12:15pm
Writing Improved Standard Operating Procedures and Troubleshooting Guides for Cores

Deedre Hayes
Industrial Extension Engineer
West Virginia University Industrial Extension/Manufacturing Extension Partnership
Participants may send their good, bad, and ugly SOPs ahead of time for possible use in this hands-on workshop. Send samples to deedre.hayes@mail.wvu.edu. Any items used will be anonymous.
NOTE: this session will be repeated in the afternoon. Content is the same for both sessions.
This two-hour workshop will offer best practices and tips for writing standard operating procedures that will elevate your documentation and avoid miscommunication that can lead to mistakes and painful downtime. Examples from MAD SSCi member cores will be used to illustrate the techniques. Participants may send their good, bad, and ugly SOPs ahead of time for possible use in this hands-on workshop. Send samples to: tkwafle@mail.wvu.edu or deedra.hayes@mail.wvu.edu. Names, addresses and other identifiers will be removed to avoid putting participants on the spot. Dee Hayes joined WVU-IE/MEP in November 2014. She works on Lean manufacturing, E3 assessment services, process simulation, and is part of the Business Evaluation service team for Transformational Services. Prior to joining WVU, Ms. Hayes worked as a project manager and director of operations for a medical device and service company in Morgantown, W.Va.
Wharf A&B, WPH
Tue
10:15am to 12:15pm
Reproducibility and Rigor Panel Disscussion

Frances Weis-Garcia, Ph.D.
Head, Antibody & Bioresource Core Facility
Memorial Sloan Kettering Cancer Center
Tim Errington Ph.D.
Metascience Manager
Center for Open Science
Mon River A&B, WPH
Tue
10:15am to 11:15am
Institutional Selling--Techniques for Getting the Attention of Administrators

Mark O. Lively, Ph.D.
Emeritus Professor of Biochemistry
Wake Forest University School of Medicine
Nicholas Ambulos, Ph.D.
Associate Professor of Microbiology and Immunology
University of Maryland School of Medicine
Salon E-H, WPH
Tue
11:15am to 12:15pm
Inter-core Collaborations

Srinivasan (Vasan) Yegnasubramanian, M.D., Ph.D.
Associate Professor of Oncology, Co-Director Experimental & Computational Genomics Core
Johns Hopkins University, School of Medicine
Sarah Wheelan, M.D., Ph.D.
Associate Professor of Oncology, Co-Director Experimental & Computational Genomics Core
Johns Hopkins University, School of Medicine
The Experimental and Computational Genomics Core (ECGC) is a newly created Core that integrates all of the cancer genomics services in the Sidney Kimmel Comprehensive Cancer Center (SKCCC). The primary mission of the Core is to allow SKCCC investigators to harness the ongoing revolution in cancer genomics to accelerate their basic discovery and translational research. The ECGC has streamlined services that were previously offered through three separate cores: the Microarray Core, Next-Generation Sequencing Core and Bioinformatics Core, into a single and clearly defined core. The services provided by the ECGC are not available elsewhere, and an SKCCC member looking to outside resources would need to independently talk with multiple vendors and would only be able to obtain piecemeal services. The ECGC provides access to, and education in, state-of-the-art, next- generation sequencing, microarray technologies and analytical workflows for probing genomic alterations (including SNVs, indels and structural alterations), cancer epigenomics (e.g., ChIP-seq and DNA methylome), transcriptomics and metagenomics. For each project, the ECGC uses a multidisciplinary clinic model to establish and execute an experimental and analytical plan, first meeting with each investigator and then helping them through all aspects of their genomics experiments, including experimental design, high-throughput microarray or next-generation sequencing workflows, and computational/bioinformatics data analysis. Additionally, the Core provides extensive educational resources, including short courses, workshops and a symposium, so that investigators can gain the skills they need to fully understand and utilize the data and analyses generated.
Salon E-H, WPH
Lunch and Exhibits
Time Presentation Title Room
Tue
12:15pm to 1:30pm
Lunch with Exhibitors

MEC Lobby
Tue
12:30pm to 1:30pm
Dare to Explore the full Spectrum with Ease: An Introduction to the IR Laser

Vashti Lacaille
Beckman Coulter
Wharf A&B, WPH
Tue
12:30pm to 1:30pm
Vendor Lunch TBD

Nanostring Technologies Inc.
Waterfront Room, WPH
Tue
12:30pm to 1:30pm
Vendor Lunch TBD

Qiagen Inc.
Mon River A&B, WPH
Tuesday Afternoon Concurrent Sessions
Time Presentation Title Room
Tue
1:30pm to 3:30pm
Writing Improved Standard Operating Procedures and Troubleshooting Guides for Cores

Deedre Hayes
Industrial Extension Engineer
West Virginia University Industrial Extension/Manufacturing Extension Partnership
Participants may send their good, bad, and ugly SOPs ahead of time for possible use in this hands-on workshop. Send samples to deedre.hayes@mail.wvu.edu. Any items used will be anonymous.
NOTE: this is a repeat of the morning session. Content is the same for both sessions.
This two-hour workshop will offer best practices and tips for writing standard operating procedures that will elevate your documentation and avoid miscommunication that can lead to mistakes and painful downtime. Examples from MAD SSCi member cores will be used to illustrate the techniques. Participants may send their good, bad, and ugly SOPs ahead of time for possible use in this hands-on workshop. Send samples to: tkwafle@mail.wvu.edu or deedre.hayes@mail.wvu.edu. Names, addresses and other identifiers will be removed to avoid putting participants on the spot. Dee Hayes joined WVU-IE/MEP in November 2014. She works on Lean manufacturing, E3 assessment services, process simulation, and is part of the Business Evaluation service team for Transformational Services. Prior to joining WVU, Ms. Hayes worked as a project manager and director of operations for a medical device and service company in Morgantown, W.Va.
Wharf A&B, WPH
Tue
1:30pm to 3:30pm
QC at the Bench

Belynda Hicks, M.S.
Deputy Director, Cancer Genomics Research Laboratory
National Cancer Institute
NOTE: this is a repeat of the morning session. Content is the same for both sessions.
Waterfront Room, WPH
Tue
1:30pm to 3:30pm
Record Keeping--How much detail do we need and why?

Debby Hollingshead, M.S.
Manager
Genomics Research Core
Tim Errington Ph.D.
Metascience Manager
Center for Open Science
Have you ever had the experience of going back to old lab notebooks and having trouble following the experiment? Tim Errington will share findings from the Reproducibility Project: Cancer Biology with a focus on issues of incomplete laboratory records. We will share experiences with deciphering incomplete records and work in small groups to review real life examples, providing feedback on strengths and areas of improvement. Participants will be asked to bring a de-identified set of records for one project from their lab.
Mon River A&B, WPH
Tue
1:30pm to 3:30pm
A Lean Approach to Lab Management

Tracy Cooper, MACc
Laboratory Manager
Vanderbilt Antibody and Protein Resource, Vanderbilt University
Most directors of Core Laboratories find themselves thrust into these positions with little or no management training. One key advantage to trained scientists for taking a lean approach to fill this gap, is familiarity of the underlying philosophy, where unlike some management trends and tools, the scientific method is deeply ingrained in Lean management. Arriving at workable solutions takes planning, experimentation, and analysis. In this workshop we will explore the basics of Lean management in a lab setting and then focus on a practical and straightforward approach to implementation of a few Lean techniques. These broad approaches to lab level project management, optimizing inventory and ordering, and ensuring proper care of equipment are applicable to a broad swath of laboratory or administrative settings. Attendees will walk away with the specific tools to begin implementation in their own working environment.
Salon E-H, WPH
Open House & Poster Reception
Time Presentation Title Room
Tue
3:30pm to 7:00pm
Exhibits Open - Hors d'oeuvre and refreshments

MEC Lobby
Tue
3:30pm to 7:00pm
Poster Viewing

MEC Lobby
Tue
4:00pm to 5:00pm
Instrumentation Advances on the Horizon

Agilent Technologies Inc., Thermo Fisher Scientific, Nanostring Technologies Inc., Advanced Analytical Technologies, Inc.
Be the first to know what innovations are coming with rapid-fire presentations directly from biomolecular vendors.
Salon E-H, WPH
Wednesday Breakfast and Exhibits
Time Presentation Title Room
Wed
8:00am to 9:00am
Vendor Breakfast TBD

Partek Inc.
Waterfront Room, WPH
Wed
8:00am to 9:00am
Breakfast with the Exhibitors

MEC Lobby
Wednesday Concurrent Sessions-1
Time Presentation Title Room
Wed
9:00am to 10:15am
Best Practices in a Flow Cytometry Shared Resource Facility

Joanne Lannigan, M.S.
Director, Flow Cytometry Core
University of Virginia School of Medicine
Monica DeLay, M.S.
Manager, Research Flow Cytometry Core
Cincinnati Children's Hospital
In November 2016 an ISAC Shared Resource Laboratory (SRL) Task Force published a document outlining a set of “best practices” for Flow Cytometry SRLs or Core Facilities to use as a general guide for achieving and maintaining standards of excellence in the services they provide. These best practices are intended as goals to achieve, and highlight several important areas that impact the efficiency, quality and reproducibility of services provided by these facilities. The following topics will be covered: 1. Introduction of the Best Practices and what is hoped to be achieved through implementation 2. Brief presentation and background information on each topic including SOPs, Training and Education, Quality Assurance, Laboratory Safety, Data Management, Staffing, and Operations 3. Identification of potential roadblocks and hurdles and how to overcome them 4. Benefits of implementation and adherence to these best practices
Waterfront Room, WPH
Wed
9:00am to 10:15am
Getting the Most from Electron Microscopy

Claudette M. St. Croix Ph.D.
Associate Professor
University of Pittsburgh
Judy King, M.D., Ph.D.
Professor of Pathology and Translational Pathobiology and Director fo the Division of Anatomic Pathology
Feist-Weiller Cancer Center, LSU Health Shreveport
In the age of decreasing money available for core electron microscopy laboratories, combining clinical services and research can be advantageous in universities with medical schools. Balancing the demands of quick clinical turn-around time and research needs is necessary. Members of the WVU Department of Pathology started an EM lab for clinical cases and research, starting with an old JEOL JEM1010 transmission electron microscope with plate film, empty lab space, and no preparatory equipment. Conversion of the TEM to digital imaging was done, and state-of-the-art preparatory equipment was purchased. Procedures were set up to successfully provide services to clients sending patient samples in for evaluation, as well as researchers needing evaluation of tissues and cells. Dr. Judy King (and Becky Radabaugh) will discuss the steps needed to set up a combined lab for clinical services and biological research needs.
Wharf A&B, WPH
Wed
9:00am to 10:15am
Getting the Most from Genomics: a Facilitated Roundtable

Kevin Gerrish, Ph.D.
Acting Director
National Institute of Environmental Health Sciences
Genomics cores operate in an increasingly complex and competitive environment. As with any core facility we support the research activities of our investigators to provide cost-effective delivery of quality data. Some of the challenges we face include but are not limited to, working with a multitude of technically challenging platforms, balancing the need of increasing our capabilities with the level of training necessary for adding them, managing the large amount of data generated using these platforms, assisting with experimental design and data analysis. The primary goal of this session is to provide a forum for discussing the common as well as unique issues that we are faced with. We hope that this discussion will provide an opportunity to establish relationships with colleagues in other core facilities that can provide technical advice, customer service hints, and other professional benefits.
Mon River A&B, WPH
Break and Exhibits
Time Presentation Title Room
Wed
10:15am to 10:45am
Break with the Exhibitors

MEC Lobby
Wednesday Concurrent Sessions -2
Time Presentation Title Room
Wed
10:45am to 12:00pm
Epigentic Studies: Progress and Pitfalls

Christine Ladd Acosta, Ph.D.
Assistant Professor
Johns Hopkins Bloomberg School of Public Health
Waterfront Room, WPH
Wed
10:45am to 12:00pm
Running an Informatics Core to Handle Variety

K. Wyatt McMahon, Ph. D.
Assistant Professor
Johns Hopkins University, School of Medicine
Wharf A&B, WPH
Wed
10:45am to 12:00pm
Core Facility Career Development Workshop

Steven K. Wendell, PhD, PC.
Director , Center for Doctoral and Postdoctoral Career Development and Assistant Professor, Department of Pharmacology & Chemical Biology
University of Pittsburgh
Salon E-H, WPH
Closing Luncheon
Time Presentation Title Room
Wed 12:15pm
Exhibits Close

MEC Lobby
Wed
12:15pm to 1:15pm
Strategies for Visualizing Large-scale Datasets in Neurosciences

George Spirou, Ph.D.
Professor of Otolaryngology, John W. and Jeannette S. Straton Research Chair in Neurosciences, Director of the West Virginia University Center for Neurosciences
West Virginia University
Salon E-H, WPH
Wed
12:15pm to 1:15pm
Best Poster Presentation

Salon E-H, WPH